73 會造成癌細胞 “thymineless death” 的抗癌藥物是:
(A) methotrexate
(B) mercaptopurine
(C) thioguanine
(D) fluorouracil
(E) A.D
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統計: A(69), B(16), C(11), D(48), E(1408) #439021
統計: A(69), B(16), C(11), D(48), E(1408) #439021
詳解 (共 8 筆)
#847905
Fluorouracil or 5-FU is a drug that is a pyrimidine analog which is used in the treatment of cancer. It is a suicide inhibitor and works through irreversible inhibition of thymidylate synthase. It belongs to the family of drugs called antimetabolites.
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#847904
Thymineless death is the phenomenon by which bacteria, yeasts and mammalian cells undergo irreversible cell death when they are starved of thymidine triphosphate, an essential precursor for DNA replication. This phenomenon underlies the mechanism of action of several antibacterial, antimalarial and anticancer agents, such as Trimethoprim, Sulfamethoxazole, Methotrexate and Fluorouracil.
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#847938
A D 都對
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#4046269
A D 抗代謝性抗癌藥
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