8. 在海馬迴(hippocampus)中,造成長期增強作用(long-term potentiation)主要是靠下列哪些受 器及離子的作用? 甲: GABA-Cl─ 乙: NMDA-Ca2+ 丙: AMPA-Na+ 丁: acetylcholine-K+
(A) 乙丙
(B) 甲乙
(C) 丙丁
(D) 甲丁
答案:登入後查看
統計: A(747), B(110), C(57), D(35), E(0) #2002547
統計: A(747), B(110), C(57), D(35), E(0) #2002547
詳解 (共 6 筆)
#4541280
長時程增強作用(LTP)


Long term potentiation
→由於同步刺激兩個神經元而發生在兩個神經元信號傳輸中的一種持久的增強現象。
→由於記憶被認為是由突觸強度的改變來編碼的,LTP被普遍視為構成學習與記憶基礎的主要分子機制之一。
海馬迴 hippocampus
→完成學習和記憶的重要器官
→短期記憶
→受器&離子:
NADA - Ca2+
AMPA - Na+


20
0
#6361176
[Glutamate receptor]
1. NMDA (N-methyl-D-aspartate) receptor
2. AMPA receptor (=non-NMDA receptor)
ㅤㅤ
16. 在腦部的海馬回(hippocampus)區域科學家觀察到一種長期增益效應(long-term potentiation),也就是神經與神經之間突觸聯繫的強度會因為外在不同的刺激程度而改變,造成這種神經突觸效率改變最主要的神經傳遞物質是?
(A) 麩胺酸(glutamate)
(B) 多巴胺(dopamine)
(C) γ-胺基丁酸(gamma-aminobutyric acid, GABA)
(D) 乙醯膽鹼(acetylcholine)
答案:A
ㅤ
55. Which of following statements concerning the mechanism of long-term potentiation (LTP) in the vertebrate brain is INCORRECT?
(A) LTP involves an increase in the strength of synaptic transmission that occurs when presynaptic neurons produce a brief, high-frequency series of action potentials.
(B) The presynaptic neuron release acetylcholine (ACh). ACh binds to its receptor, opening the receptor channel and depolarizing the postsynaptic membrane.
(C) Ca2 + diffuses into the postsynaptic neuron. Ca2 + initiates the phosphorylation of the receptor, making them more responsive.
(D)
stimulates the postsynaptic neuron to produce NO.
(E) NO diffuses into the presynaptic neuron, causing it to release more neurotransmitters.
答案:B
ㅤㅤ
9. Which one is NOT involved in long-term potentiation of the brain?
(A) Glutamate
(B) Mg2+, Na+, Ca2+
(C) NMDA receptor
(D) AMPA receptor
(E) P granules
答案:E
ㅤㅤ
27. 長期增強作用(long-term potentiation, LTP)最早是在大腦哪一個區域被發現?
(A) 基底核
(B) 大腦皮質
(C) 杏仁核
(D) 海馬迴
答案:D
ㅤㅤ
0
0