試題詳解

17. Which of the following description about RNA polymerase II (Pol II) is (are) correct?
(A) Pol II is a multiprotein complex that transcribes DNA into precursors of mRNA and microRNA.
(B) The C-terminal domain (CTD) of the RNA polymerase binding protein (Rpb1) subunit of Pol II interacts with the splicing factor and stimulates splicing of substrates in organisms that use exon definition.
(C) The facilitates chromatin transcription (FACT) complex is a histone chaperone comprising Spt16 and SSRP1, which is involved in transcription elongation by RNA polymerases II.
(D) The CTD of the Rbpl subunit is involved in capping and splicing but not in polyadenylation.
(E) The cotranscriptional cleavage (CoTC) element is essential for transcription termination.