1.Phenoxybezamine與α1 受體的結合可被視為:
(A)全致效劑(full agonist)
(B)部分致效劑(partial agonist)
(C)競爭性拮抗劑(competitive antagonist)
(D)非競爭性拮抗劑(non-competitive antagonist)

答案:登入後查看
統計: A(513), B(438), C(1198), D(1248), E(0) #1944271

詳解 (共 6 筆)

#3188447
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#3463718
Phentolamine:診斷嗜鉻細胞瘤
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Phenoxybenzamine:治療嗜鉻細胞瘤、治療高血壓(易有姿勢性低血壓)、共價結合
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#3467071

補充一下,在綠皮 Phenoxybenzamine 是α1拮

但在紅皮原文書它是α1>α2的非選擇性拮抗劑

The α-adrenergic antagonistic effects of phenoxybenzamine are more substantial with α1- than α2-adrenergic receptors.

Phenoxybenzamine demonstrates a variety of other pharmacological effects including inhibiting the reuptake of NE at presynaptic nerve terminals and acting to various degrees as an antagonist at histamine, acetylcholine, and serotonin receptors.

The predominant, and perhaps only, use of phenoxybenzamine in veterinary medicine is to manage the symptoms of catecholamine excess in the treatment of patients with a pheochromocytoma.

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#5885595
不可逆共價鍵與a1結合==>增加a...
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#5535977


來源: Veterinary Pharmacology and Therapeutics, 10th
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私人筆記 (共 2 筆)

私人筆記#1530511
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Phenoxybenzamine補充說明...
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私人筆記#5944666
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Phenoxybezamine是α1受體...
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