11. Which of the following is the unacceptable statement about postoperative pain related to acute pain mechanisms? (A) A decrease in the nociceptor threshold is due to changes in the transducers themselves (autosensitization). (B) An increase in the excitability of the terminal membrane is initiated by sensitizing agents (heterosensitization). (C) Enhanced responsiveness of central pain transmission neurons is due to wind-up. (D) Enhanced responsiveness of central pain transmission neurons is due to facilitated synaptic responses. (E) Enhanced responsiveness of central pain transmission neurons is due to increase inhibition.