15. Thymine nucleotides are not synthesized directly by cells but indirectly from other pyrimidine deoxyribonucleotides. All of the following statements regarding thymine nucleotide synthesis are true EXCEPT: (A) dUMP is the immediate precursor for dTMP, (B) The action of dUTPase allows dUTP to serve as a substrate in DNA synthesis, (C) Thymidylate synthase catalyzes the formation of dTMP from dUMP, (D) The methyl donor in the reaction of dTMP is N5, N10-methylene-THE, (E) THF is used as a cofactor.