試題詳解

2. A single nucleotide deletion occurred in a gene. The change is indicated below. What is the consequence of the mutation?
......AGT CGA TGA GTT AGC CTA...... → ......AGT CGA TGG TTA GCC......
(A) The mutation occurs in the third position of a codon so it is likely to be a silent mutation because of the Wobble effect.
(B) It leads to frameshift so the downstream amino acid sequence will alter and the protein is unlikely to be functional.
(C) It results in premature termination of translation so a truncated polypeptide will be produced.
(D) A longer polypeptide will be made but the protein might still be functional.
(E) It changes the single amino acid, which may or may not cause a problem.