22 下列有關 spironolactone 之敘述,何者錯誤?
(A)是 aldosterone 的競爭型拮抗劑
(B)在肝臟代謝後的主要活性代謝物為 canrenone
(C)結構中有一個內酯環
(D)結構中的-SCOCH 3 基團位於 6α 上

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統計: A(15), B(45), C(11), D(209), E(0) #412801

詳解 (共 3 筆)

#1287672
(D)結構中的-SCOCH 3 基團位於7α
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#5567785

(B)Canrenone is an active metabolite of spironolactone with a long half-life, which is currently available only in Europe. Canrenone has been shown to improve diastolic function in patients with primary hypertension independently of effects on BP and LV mass regression, suggesting a direct myocardial effect.


https://www.medscape.com >

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#5751957
Spironolactone 是 Al...


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