22.Goodpasture's syndrome主要病變發生在下列那些器官?①肝臟 ②肺臟 ③腎臟 ④心臟
(A)①②
(B)②③
(C)③④
(D)①③
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統計: A(40), B(575), C(142), D(252), E(0) #670825
統計: A(40), B(575), C(142), D(252), E(0) #670825
詳解 (共 3 筆)
#1466505
Goodpasture syndrome is an eponym that has been used to describe the clinical entity of diffuse pulmonary hemorrhage (as seen in the images below) and acute or rapidly progressive glomerulonephritis. Goodpasture disease is a term used to describe glomerulonephritis, with or without pulmonary hemorrhage, and the presence of circulating anti–glomerular basement membrane (anti-GBM) antibodies. The definitions of these terms have not been consistent, however. Anti-GBM disease, a more precise term, should be used to refer to either of the two distinct clinical manifestations of this disorder.
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#5482678
Goodpasture’s syndrome
-屬於自體免疫疾病
-由抗腎絲球基地膜抗體anti-GBM(anti-glomerular basement membrane antibodies)引起
-誘發第二型過敏反應,引起腎絲球腎炎
-結合肺泡基地膜導致肺泡病變,痰液中的巨噬細胞含有hemosiderin
-與HLA-DR2有高度相關性
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