25 Mantle cell lymphoma 最常出現的染色體異常為何？
(A) t(11; 14)
(B) t(9; 22)
(C) t(15; 17)
(D) trisomy 12

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統計： A(775), B(53), C(61), D(44), E(0) #704860

詳解 (共 2 筆)

#1106114
MCL is a subtype of B-cell lymphoma, due to CD5 positive antigen-naive pregerminal center B-cell within the mantle zone that surrounds normal germinal center follicles. MCL cells generally over-express cyclin D1 due to a t(11:14)chromosomal translocation in the DNA. More specifically, the translocation is at t(11;14)(q13;q32).
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#4103896
(A) t(11; 14)-Mantle...
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