試題詳解

26. Which of the following statement related to the nuclear receptor is       not true      ?
(A) Thyroid hormone receptor belongs to type I receptors, which stay in the cytoplasm in the absence of its ligand
(B) Type III receptors are "orphan" receptors whose ligands are not yet identified
(C)In the presence of ligand, the glucocorticoid receptor (GR) can form a homodimer within the nucleus
(D)In the absence of ligand, GR exists as an inactive form in cytoplasm complexed with the heat shock protein 90 (Hsp90)
(E) Nuclear receptors interact with different endocrine-signaling molecules and activate gene expression via its binding to hormone response DNA elements