30 下列有關 digoxin 進行藥物濃度監測(TDM)之敘述,何項錯誤?
(A)其抽血取樣時間以給藥後 6 小時以內為宜
(B)其體清除率與腎功能呈正比關係
(C)對肥胖病人其劑量應依病人之理想體重估算
(D)在治療心衰竭(CHF)時較治療心房顫動(AF)所需達到之穩定濃度為低
答案:登入後查看
統計: A(221), B(39), C(47), D(27), E(0) #415537
統計: A(221), B(39), C(47), D(27), E(0) #415537
詳解 (共 5 筆)
#894515
Digoxin concentrations should be measured at least eight hours following an oral dose of digoxin and ideally when concentrations have reached steady-state.
19
3
#4929611
心衰竭(CHF): 0.5-1 ng/mL
心房顫動(AF): 0.8-2 ng/mL
3
0
#5952904
Digoxin的抽血時間:給完藥6小時後,最好大於12小時。
Dipro 12e課本原文:「Digoxin pharmacokinetics are well described. There is a long “distribution phase” after administration of oral or IV digoxin, resulting in a lag time before a maximum pharmacologic response is observed. Blood samples for measurement of SDCs should be collected at least 6 hours and preferably 12 hours or more after the last dose.」
1
0
#2887875
hf:0.5-1.0ng/ml
af:1.0-2.0ng/ml
1
3
#5761279
63.毛女士62歲,經診斷為心衰竭給與digoxin 0.25 mg PO QD處方;使用數日後預估藥品血中濃度達steady state,如擬進行療劑監測,則最佳抽血時機為何?
(A) 給藥後約1小時
(B) 給藥後約3小時
(C) 給藥後約6小時
(D) 下次給藥前
答案:D
1
0