試題詳解

36. Which of the following statement concerning "cytokines" is least likely:
(A) Cytokines mediate the communication from the immune system to the peripheral nervous system and CNS, and to endocrine systems
(B) IL-1, IL-6 and TNF-α are pro-inflammatory cytokines
(C) Intraperitoneal injection of IL-1β in rats generate hyperalgesia that can not be abolished by vagotomy
(D) Bradykinin activates macrophages that release TNF-α, which sensitizes nociceptors by the production of IL-6 and IL-1β
(E) IL-6 and TNF-α, released intraneurally by macrophages, are involved in neuropathic pain