38._____________ , a pathway that synthesizes glucose from non-carbohydrate precursors, uses seven of the same enzymes as glycolysis, but must replace three enzymes of glycolysis because they are_____________ .
(A) Catabolism; to oxidative
(B) Gluconeogenesis; irreversible
(C) Oxidative phosphorylation; reductive
(D) Gluconeogenesis; anabolic
(E) Oxidative phosphorylation; irreversible
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