39 Actinomycin D 與下列何種抗癌藥同具 DNA intercalation 作用?
(A) Methotrexate
(B) Adriamycin
(C) Bleomycins
(D) Cyclophosphamide
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統計: A(8), B(68), C(41), D(32), E(0) #418305
統計: A(8), B(68), C(41), D(32), E(0) #418305
詳解 (共 7 筆)
#854698
Actinomycin D是一種抗癌性抗生素,其phenoxazone chromophore可與雙股DNA形成intercalation, 也可以雙股peptide lactone 鍊藉著氫鍵與疏水性的交互作用,結合到DNA 的小槽
10
0
#843269
Cyclophosphamide->4-Hydroxycyclophosphamide->Phosphoramide Mustard+Acrolein
Phosphoramide Mustard轉化為Aziridinium ion 烷化DNA
5
1
#854689
Dactinomycin, is the most significant member of actinomycines, which are a class of polypeptide antibiotics isolated from soil bacteria of the genus Streptomyces. As one of the older chemotherapy drugs, it has been used for many years.
2
0
#5840326
Bleomycin不是也會嵌入DNA嗎?
0
0