39. The Sanger sequencing procedure uses dideoxynucleoside triphosphate (ddNTP) analogs to interrupt DNA synthesis. When a ddNTP is inserted in place of a dNTP, the strand elongation is halted, because it:
(A) lacks the 5'-phsophate group needed for the next step.
(B) lacks the 2'-hydroxyl group needed for the next step.
(C) lacks the 3'-hydroxyl group needed for the next step.
(D) possesses the additional 2'-hydroxyl group, which interrupts DNA synthesis.

(E) possesses the additional 3'-hydroxyl group, which interrupts DNA synthesis.

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