40. It is crucial that regulation occur at pyruvate dehydrogenase because:
(A) pyruvate kinase is reversible
(B) lactate dehydrogenase is the only other enzyme to use pyruvate
(C) the product acetyl-CoA is committed to oxidation in the citric acid cycle or fatty acid biosynthesis
(D) alanine aminotransferase would use the pyruvate
(E) all of the above
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