44.下列何種藥品係因為肝毒性而下架?
(A)troglitazone
(B)terfenadine
(C)rofecoxib
(D)cisapride

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統計: A(1210), B(265), C(129), D(85), E(0) #416638

詳解 (共 6 筆)

#987312

Troglitazone (Rezulin) 產生肝毒性

Rosiglitazone ( Avandia ) 產生心臟毒性

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#892551
(A)troglitazone 產生肝毒性 
(B)terfenadine 產生心臟毒性 
(C)rofecoxib 產生心臟、血管毒性 
(D)cisapride 產生心臟毒性 
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#892538
33.Troglitazone在美國上市後,卻於2000年3月被回收停產的原因為何? 
(A)產生心臟、血管毒性 
(B)產生肝毒性 
(C)產生腎毒性 
(D)產生血液毒性
專技高考◆藥師◆調劑學與臨床藥學- 092-檢覈2-藥師-調劑學(包括臨床藥學及治療學)#15149
答案:B
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#3494974

1. 心血管風險:

Rofecoxib、Sibutramines(諾美婷)、Tegaserod

 

2. 危及生命之心律不整:

Cisapride、Terfenadine、Astemizole

 

3.出血性腦中風:

Phenylpropanolamine(PPA)

 

4. 腎衰風險:

Aristolochic acid

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#806727
Troglitazone (Rezulin, Resulin, Romozin, Noscal) is an antidiabetic and anti-inflammatory drug, and a member of the drug class of the thiazolidinediones.
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#6515140
Troglitazone: 硫酸結合為主...
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