48. A 45-year-old woman discovers a painless, firm, mobile mass in the upper outer quadrant of her right
breast. Mammography shows a well-circumscribed, radiodense lesion. Excisional biopsy reveals a
well-demarcated, biphasic tumor composed of epithelial-lined glandular spaces and aproliferating
cellular stroma. The lesion lacks significant cytologic atypia and mitotic activity. Which of the
following is the most likely diagnosis?

(A) Fibroadenoma
(B) Invasive ductal carcinoma of no special type

(C) Intraductal papilloma
(D) Phyllodes tumor, high grade