48. Which one of the following statement about central pain is wrong?
(A) Central pain involves plasticity in a single area of CNS.
(B)Sensitization of the CNS plays a major role in central pain and involves neuronal hyper-excitability resulting in an increased response to synaptic inputs, decreased threshold, expansion of receptive fields, and access of low-threshold Aβ mechanoreceptors to pain pathways.
(C) The clinical consequences of central pain are allodynia, hyperalgesia, and after-sensations.
(D) Central sensitization may also include spontaneous discharges.
(E) Spontaneous discharges in damaged pain pathways or deafferented rostral neurons may be responsible for spontaneous ongoing or intermittent pain.

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