49.下列何種抗體常用來確認腫瘤為上皮細胞起源？
(A)anti-cytokeratin
(B)anti-desmin
(C)anti-MHC class I
(D)anti-MHC class II

Immunohistochemistry for specifc cell markers may be used to aid in the diagnosis of some tumors. For example, immunohistochemistry is commonly used to determine if a lymphoma originates from B or T lymphocytes (E-Fig. 6-3). This knowledge may be useful to the clinician in designing treatment or delivering a prognosis.

The type of intermediate flaments present in an undifferentiated malignancy can indicate if the tumor is of epithelial (positive for cytokeratin staining) or mesenchymal (positive for vimentin staining) origin. Some neoplasms, such as mesotheliomas and synovial cell sarcomas, are often positive for both cytokeratin and vimentin.  

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