試題詳解

49. Which of the following descriptions for Transdermal therapeutic system fentanyl (fentanyl-TTS) patches is not correct after application?
(A) a lag time of approximately 2 hours before plasma levels of fentanyl are detected and detected therapeutic levels after 12 to 16 hours
(B) After system removal, serum fentanyl concentrations decline gradually and has an apparent t1/2 of 17 hours
(C) Prolonged exposure to heat or use in patients who are febrile can cause a toxic overdose
(D) should not be used in patients who are not opioid-tolerant, for acute pain issues
(E) All of the above are correct descriptions