50. Descending inhibitory pathways typically involve which of the following neurochemical mechanisms EXCEPT?
(A) Noradrenergic
(B) Enkephalinergic
(C) Serotonergic
(D) Cholinergic

46. Which of the following statements regarding corticosteroid use is NOT true? (A) 30-50% of patients on chronic oral corticosteroid therapy suffer from osteoporotic fractures. (B) Corticosteroid users are at increased risk of NSAID-related GI bleeding. (C) Corticosteroid use can be associated with weight gain, hypertension and hyperglycemia. (D) Osteoporosis is only a concern in patients who have been on corticosteroids for over 12 months.

47. Which statement about Trigeminal autonomic cephalgias (TAC) is wrong? (A) Oxygen inhalation is a safe and effective method for acute treatment of cluster headache (B) Midbrain and pontine activation play a pivotal role in either initiation or termination of the acute attack of migraine (C) The forehead, temporal, orbit and occiput are the most frequent sites of hemicrania continua (D) Paroxysmal hemicrania responds in a dramatic and absolute fashion to indometacin (E) Short-lasting unilateral neuralgiform headache with conjunctival injection and tearing (SUNCT) syndrome is usually maximal in the ophthalmic distribution of trigeminal nerve

48. Tension-type headache (TTH) is an ill-defined and heterogeneous syndrome. Hence, its managements are associated multiple models. Which statement is wrong? (A) Combination of analgesic with muscle relaxants is the most effective therapy with scientific evidence (B) Ibuprofen can be considered the first choice for TTH (C) Tricyclic antidepressants are the most widely used first-line therapeutic and prophylactic agents (D) Relaxation and EMG biofeedback therapies have been proven to treat TTH (E) The adjunction of caffeine significantly increases the efficacy of ibuprofen only

49. As we know, bone scan is the most common diagnostic tool for bone metastasis. Which limitation is incorrect? (A) Bone scan is characterized by high sensitivity and high specificity (B) Any positive findings should be corresponded to painful sites with further evaluation of CT or plain radiographs (C) Bone scan doesn't evaluate the structural integrity (D) Most common pattern of metastasis in bone scan is "hot spot" with radioisotope accumulation for new bone reaction (E) Some cancers may not show "hot spot" pattern, such as melanoma and multiple myeloma

四、文意排序與翻譯:請依文意將下列兩小題中的文句,選出排列順序最適當的選項,並請翻譯之 1.排序、翻譯世之所貴道者,書也,書不過語。 甲、而世因貴言傳書, 乙、意有所隨,意之所隨者,不可以言傳也, 丙、世雖貴之,我猶不足貴也, 丁、語有貴也,語之所貴者,意也, 為其貴非其貴也。(《莊子·天道》) (A)甲丙丁乙 (B)乙甲丁丙 (C)丙丁乙甲 (D)丁乙甲丙

2.排序、翻譯「危微之幾,惟明君子而後能知之。故人心譬如槃水, 甲、微風過之 乙、正錯而勿動 丙、則足以見鬚眉而察理矣 丁、湛濁動乎下,清明亂於上 戊、則湛濁在下,而清明在上 則不可以得大形之正也。」(《荀子·解蔽》) (A)甲丁乙戊丙 (B)甲戊丙乙丁 (C)乙戊甲丁丙 (D)乙戊丙甲丁

(一)請依格律及詩意仔細推敲,選出最適合填入口內的選項是: (A)思孟顏會俎豆旁(B)頑儒羞登夫子堂 (C)今來誰識東歸意(D)莓苔多處古宮牆

(二)承上題,此首七律的題目〈○○○○〉,最適合的選項是: (A) 題孔子廟 (B) 謁三閭祠 (C) 題夷齊廟(D) 祭太史公

(三)下列是一段古文,請依文意選出排列順序最恰當的選項:  「夫治膏肓者, (甲)必告逆耳之言 (乙)如其迷謬,未知所投 (丙)必進苦口之藥 (丁)恐俞附見其已困 (戊)決狐疑者 扁鵲知其無功也!勉思良圖,惟所去就。」  (孫子荆〈爲石仲容與孫皓書〉) (A) 甲戊丙丁乙(B)乙丙戊甲丁(C)丙戊甲乙丁(D)丁丙戊乙甲

 (一)請依格律及詩意仔細推敲,選出最適合填入口內的詞語,依序是: (○○〈九月三日泛舟湖中作〉) (A)涼/綠樹/荷夕陽 (B)霜/紅樹/過重陽 (C)妝/黃髮/總鄕愁 (D)香/楓紅/夢歸鄉