67 裸鼠（nude mice）有嚴重的免疫缺損，請問裸鼠的免疫缺損和下列那一種人類的疾病最類似？
(A) DiGeorge syndrome
(B) common variable immunodeficiency
(C) severe combined immunodeficiency
(D) Omenn syndrome

DiGeorge syndrome 

DiGeorge syndrome is a genetic disorder caused by the deletion of a small section of chromosome 22. This results in a midline congenital defect including thymic aplasia, or congenital deficiency of a thymus. Patients may present with a profound immunodeficiency disease, due to the lack of T cells. No other immune cell lineages are affected by the congenital absence of the thymus. DiGeorge syndrome is the most common congenital cause of thymic aplasia in humans. In mice, the nude mouse strain are congenitally thymic deficient. These mice are an important model of primary T cell deficiency.