67 有關王老先生血脂異常之處置,下列口服處方中,何者是首選?
(A) Cholestyramine 4 g tid
(B) Lovastatin 80 mg hs
(C) Niacin ER 1 g hs
(D) Pravastatin 20 mg qd
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統計: A(11), B(72), C(12), D(111), E(0) #416421
統計: A(11), B(72), C(12), D(111), E(0) #416421
詳解 (共 5 筆)
#1075128
口服Pravastatin,主要透腸肝循環排出,腎臟排出極少,適用於腎功能不佳之病患。
15
1
#2898962
Pravastatin is the statin of choice in patients on cyclosporine.
uptodate還特地把上述列成單獨一點!!
The risk is substantially increased for most statins extensively metabolized by cytochrome P450 3A4 (lovastatin, simvastatin and to a lesser extent atorvastatin) with concurrent therapy with drugs that interfere with CYP3A4
Pravastatin, fluvastatin, rosuvastatin, and pitavastatin are preferred when concurrent therapy with a strong inhibitor of CYP3A4 cannot be avoided.
8
0