7.有關iron refractory iron deficiency anemia（IRIDA）的敘述，下列何者錯誤？
(A)大多是autosomal recessive的遺傳疾病
(B)口服與靜脈注射的鐵劑通常毫無效果
(C)可因TMPRSS6基因突變所致
(D)血漿中的hepcidin通常是升高的

Iron refractory iron deficiency anemia is a hereditary recessive anemia due to a defect in the TMPRSS6 gene encoding Matriptase-2. This protein is a transmembrane serine protease that plays an essential role in down-regulating hepcidin, the key regulator of iron homeostasis.
Hallmarks of this disease are microcytic hypochromic anemia, low transferrin saturation and normal/high serum hepcidin values.
 參考資料:　https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669438/

課本p.46，靜脈注射鐵劑可能有血液學反應，但口服鐵劑無效。