73.下列何者與imatinib併用時,會使imatinib血中濃度下降?
(A)amiodarone
(B)clarithromycin
(C)St. John’s wort
(D)verapamil
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統計: A(56), B(105), C(2206), D(70), E(0) #3197771
統計: A(56), B(105), C(2206), D(70), E(0) #3197771
詳解 (共 4 筆)
#6163625
From 前人
23
5
#6337622
imatinib為3A4.2C6.2C19受貭
找P450 agonist 促進代謝
10
0
#6508679
St. John’s wort can weaken the effects of many medicines, including crucially important medicines such as:
- Some antidepressants, including amitriptyline and bupropion
- Birth control pills
- Cyclosporine, which prevents the body from rejecting transplanted organs
- Some drugs used to prevent seizures, including phenytoin and carbamazepine
- Some heart medications, including digoxin and ivabradine
- Some HIV drugs, including indinavir and nevirapine
- Some cancer medications, including irinotecan, imatinib, and docetaxel
- Warfarin, an anticoagulant (blood thinner)
- Certain statins, including simvastatin
來自NIH
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