阿摩線上測驗
79.下列有關zinc phosphide殺鼠劑的敘述中，何者正確？
(A)於胃內酸性環境中，很穩定而不會被水解
(B)空腹較飽食時易增加口服毒性
(C)可使胃內容物具有乙炔的味道
(D)最常使用pralidoxime解毒
答案：登入後查看
統計： A(112), B(296), C(627), D(414), E(0) #853842
統計： A(112), B(296), C(627), D(414), E(0) #853842
詳解 (共 7 筆)
Noel Ng
#4841145
治療方向：
催吐
制酸
活性碳
acetylcysteine
保肝
抗痙攣
Management of zinc phosphide ingestion relies on effective decontamination. If the animal has not already vomited, emesis can be induced by use of apomorphine. Decreasing gastric acid may be beneficial, via oral magnesium hydroxide antacid or using famotidine at 1 mg/kg, SC. IV fluid support is recommended while the animal is under observation. Use of activated charcoal may be considered; although metals are poorly bound by activated charcoal, the larger zinc phosphide molecule may be. If vomiting is ongoing, administration of activated charcoal should be avoided because of the aspiration risk. Obtaining a baseline biochemical profile, with repeat evaluation of liver and renal values at 24, 48, and possibly 72 hr, is recommended. Use of N-acetylcysteine may be beneficial, with a loading dose of 140 mg/kg, followed by 70 mg/kg every 6 hr for six total doses. Administration of S-adenosyl methionine (SAM-e) may also be beneficial. Seizures should be controlled with diazepam or barbiturates, and other signs treated symptomatically.
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