79.有關犬腎上腺功能低下,何者錯誤?
(A)又稱Addison's disease
(B)與自體免疫攻擊腎上腺髓質有關
(C)因腎上腺束狀帶和網狀帶細胞數量不足所導致
(D)僅少數患犬會呈現正常的血鈉與血鉀值
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統計: A(29), B(1422), C(429), D(199), E(0) #2743769
統計: A(29), B(1422), C(429), D(199), E(0) #2743769
詳解 (共 5 筆)
#5560398
(D)機制小複習
低腎上腺功能>少了醛固酮(留鈉排鉀)作用>鈉排出增加/鉀排出下降>高血鉀、低血鈉
另外: 糖皮質激素(glucocorticoid)缺乏,會致糖質新生作用失靈和對胰島素的敏感度上升而引起低血糖
抱歉沒時間翻譯 直接節錄下來
Addison's disease
- young adult to middle-aged dogs with slight female predominance
- The histologic lesions of Addison’s disease are lymphoplasmacytic adrenalitis and severe lytic destruction of all three layers of the adrenal cortex.
- 少數的狗,the zona glomerulosa (球狀帶分泌礦皮質固醇)is at least partially spared(幸免於難); these dogs may have normal serum concentrations of sodium and potassium.
- Without mineralocorticoid and glucocorticoid replacement therapy, destruction of the adrenal cortices is fatal. However, treated dogs can live with Addison’s disease for years
病理原文書p.720
結構小複習
由上而下(球>束>網)
球狀帶(Zona glomerulosa): 礦皮質固醇(如 醛固酮)佔皮質厚度15%
束狀帶(Zona fasciculata): 糖皮質固醇 佔皮質厚度78%
網狀帶(Zona reticularis): 雄性素
我都記"球網" /"束"的字型有一個在中間的型態;
球況(球狀帶: 礦皮質固醇); 其他就空間記憶吧
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#6460237
提供給跟我一樣記不清楚腎上腺皮質分層順序的人,畫一朵花,從上而下剛好是球-束-網(球狀帶-束狀帶-網狀帶)

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