79.犬類風濕性關節炎(rheumatoid arthritis),浸潤關節滑膜的炎症細胞主要為:
(A)嗜中性球和巨噬細胞
(B)嗜中性球和嗜酸性球
(C)肥大細胞和嗜酸性球
(D)淋巴球、漿細胞及巨噬細胞
統計: A(634), B(200), C(182), D(954), E(0) #828503
詳解 (共 3 筆)
終於查到了,實診跟病理都沒錯,因為實診是在講關節囊液,而這題病理是在問浸潤關節滑膜,詳情如下:
"However, unlike the rheumatoid synovial tissue in which the infiltrating cells are lymphocytes and macrophages but not neutrophils, in synovial fluid the predominant cell is the neutrophil."---https://www.hopkinsarthritis.org/arthritis-info/rheumatoid-arthritis/ra-pathophysiology-2/
延伸閱讀:
像在古老的這篇 Immune-based erosive inflammatory joint disease of the dog: canine rheumatoid arthritis 就有提到他用人類的criteria來診斷犬類風濕性關節炎,其中一項講到組織病理 "Characteristic histopathological changes in the synovial membrane with three or more of the following: marked villous hypertrophy, proliferation of superficial synovial cells, marked infiltration of chronic inflammatory cells (lymphocytes and plasma cells predominating) with tendency to form 'lymphoid nodules', deposition of fibrin, foci of cell necrosis."
而最後 synovial fluid analysis 的實驗結果顯示有多量白血球,是以polymorphonuclear cells為主。
順帶一提,類風濕性關節炎是第三、第四型過敏反應。