80.下列何者異常為導致骨生成不全(osteogenesis imperfecta)的主要原因?
(A)礦物質
(B)第一型膠原蛋白
(C)骨骺板的軟骨細胞
(D)非膠原蛋白
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統計: A(389), B(1052), C(1039), D(46), E(0) #1587886
統計: A(389), B(1052), C(1039), D(46), E(0) #1587886
詳解 (共 7 筆)
#3768877
The five most common collagen types are:
Type I: skin, tendon, vasculature, organs, bone (main component of the organic part of bone)
Type II: cartilage (main collagenous component of cartilage)
Type III: reticulate (main component of reticular fibers), commonly found alongside type I
Type IV: forms basal lamina, the epithelium-secreted layer of the basement membrane
Type V: cell surfaces, hair, and placenta
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#3768723
Many cases of Osteogenesis imperfecta (estimated 90% of cases in human and veterinary medicine) are associated with mutations in COL1A1 or COL1A2, which are genes that encode the pro-α1 or pro-α2 chains of type 1 procollagen.
病理第六版p973
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