(4) Can enzymes make a nonspontaneous reaction occur? Why or why not? (3%) [Image of reaction energy diagrams A and B]

6. Particulate matter (PM) pollution is a serious problem in environmental medicine. What are the definitions of PM10, PM2.5 and PM1.0? What are the compositions of these PMs? How PM10, PM2.5 and PM1.0 affect people's health? What are the relationship between these PMs and lung cancer and cardiovascular disease? (10%)