6. Illustrate the key points of regulation in the biosynthesis of (a) IMP, (b) AMP & (c) GMP (d) E.coli pyrimidine biosynthesis (e) mammalian pyrimidine biosynthesis? (10%)

3. Ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) is the core autotrophic carboxylase in all oxygenic photosynthetic organisms. Rubisco activase (Rca) adjusts the rate of CO2 fixation to the rates of electron transport activity via the reactivation of inhibited Rubisco. Please elaborate how different factors (e.g., ribulose-1,5- bisphosphate, CO2, Mg2+, and ATP) participate in the process before or after reactivation of Rubisco mediated by Rca? (10%)

6. Illustrate the key points of regulation in the biosynthesis of (a) IMP, (b) AMP & (c) GMP (d) E.coli pyrimidine biosynthesis (e) mammalian pyrimidine biosynthesis? (10%)

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