試題詳解

27. Which of the following descriptions regarding transcription is (are) CORRECT?
(A) The TATA box sequence is present in the promoter region in eukaryotes and is important for transcription initiation.
(B) The phosphorylation status of the CTD (C-terminal domain) of RNA polymerase II distinguishes the stages of transcription, including initiation, elongation, and termination.
(C) Most eukaryotic coding genes end with a poly（Ａ） sequence in their genomic DNA.
(D) At the end of eukaryotic RNA polymerase II transcription, a ribonuclease cleaves the newly synthesized RNA downstream of the polyadenylation signal, initiating RNA processing and transcription termination.
(E) The mRNA 5' methylated cap is 7-methylguanylate linked to the first nucleotide of the RNA via a regular phosphodiester bond as in other regions of the RNA backbone.