試題詳解

複選題
33. Which of the following features are correct regarding the mechanism of DNA polymerase?
(A) DNA polymerase uses a single active site to catalyze the addition of any of the four deoxynucleoside triphosphates.
(B) Steric constraints prevent DNA polymerase from using ribonucleoside triphosphates as substrate.
(C) The thumb domain of DNA polymerase is intimately involved in catalysis.
(D) Processivity is a crucial character for DNA polymerase and defines the average number of nucleotides added per template binding event.
(E) Removal of incorrectly base-paired nucleotides is mediated by intrinsic endonuclease activity of DNA polymerase.