10. Which of the following is not a contiguous membrane domain?
(A) Rough ER
(B) Nuclear envelope
(C) Smooth ER
(D) Transitional ER
(E) Secretory granules

6. The proofreading property of DNA polymerase is due to its ______ activity. (A) 3' to 5' exonuclease (B) 5' to 3' exonuclease (C) excision repair (D) mismatch repair (E) endonuclease

7. Small interfering RNAs repress transcription by ______. (A) binding to and cleaving the gene. (B) binding to and methylating the DNA of the gene. (C) hybridizing with and blocking transcription of a gene. (D) hybridizing with a nascent mRNA and binding a RITS complex, which condenses the chromatin of a gene. (E) All of the above

8. Eukaryotic ribosomes recognize and initially bind to what structure on the mRNA? (A) A Shine-Dalgarno sequence (B) The 7-methylguanosine cap (C) A TATA sequence (D) An AUG initiation codon (E) A CAT sequence

9. The nuclear localization signal is recognized by and binds to which protein in the process of nuclear protein import? (A) Ran (B) Exportin (C) Importin (D) Nucleoporin (E) The outer fibril protein

11. Most higher eukaryotic plasma membrane proteins are synthesized on ______. (A) free ribosomes and inserted after translation into the plasma membrane (B) ribosomes associated with the plasma membrane and inserted into the membrane cotranslationally (C) smooth ER and carried to the plasma membrane by vesicles that pinch off from the Golgi apparatus (D) rough ER ribosomes and carried to the plasma membrane by vesicles that pinch off from the rough ER (E) rough ER ribosomes and carried to the plasma membrane by vesicles that pinch off from the Golgi apparatus.

12. Most mitochondrial proteins are synthesized on ______. (A) mitochondrial ribosomes from nuclear mRNAs (B) mitochondrial ribosomes from mitochondrial mRNAS (C) cytoplasmic ribosomes from mitochondrial mRNAs (D) cytoplasmic ribosomes; they are imported after they are completely synthesized (E) cytoplasmic ribosomes; they are imported cotranslationally as they are being synthesized

13. Electron transport and oxidative phosphorylation are performed by protein complexes in the mitochondrial ______. (A) inner membrane (B) outer membrane (C) intermembrane space (D) matrix (E) Both a and c

14. The GTP bound to ẞ-tubulin hydrolyzes to GDP and Pi ______. (A) during formation of the α-β dimer (B) during polymerization of dimers onto microtubules (C) following polymerization but before depolymerization (D) during depolymerization of dimers from microtubules (E) following depolymerization of dimers from microtubules

15. Intermediate filaments function in ______. (A) cell motility (B) providing mechanical strength for cells (C) nuclear pore structure (D) All of the above (E) None of the above

16. Active transport is transport ______. (A) of all molecules simultaneously, against their concentration gradients, across the membrane (B) in an energetically favorable direction coupled to the hydrolysis of ATP (C) in an energetically unfavorable direction always driven by hydrolysis of ATP (D) in an energetically unfavorable direction always coupled to another reaction or source of energy (E) in an energetically unfavorable direction driven only by the flow of another molecule across a membrane