12 下列抗黴菌藥物中，何者以間歇療法（pulse therapy），即每一療程先服藥一星期後停藥三星期治療灰指甲（甲癬）為較佳的治療方式？
(A) itraconazole
(B) griseofulvin
(C) ketoconazole
(D) terbinafine

答案：登入後查看
統計： A(194), B(106), C(10), D(139), E(0) #412871

詳解 (共 5 筆)

#887294
itraconazole 200mg bid 先服藥一星期後停藥三星期。
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#3412670
Itraconazole為azole類抗...
(共 107 字，隱藏中）
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#2886932

itraconazole

Onychomycosis in Non-immunocompromised Patients Fingernails: 2 treatment pulses, each consisting of 200 mg q12hr for 1 week Toenails, with or without fingernail involvement: 200 mg/day PO for 12 weeks


ketoconazole

Avoid prescribing tablets to treat skin and nail fungal infections owing to risk of serious liver damage, adrenal gland problems, and harmful interactions with other medicines that outweigh its benefit in treating these conditions, which are not approved uses of the drug (these indications were removed from labeling by the FDA in 2013)


terbinafine

Onychomycosis

Indicated for onychomycosis of the toenail or fingernail owing to dermatophytes (tinea unguium

250 mg (1 tablet) PO daily for 6 weeks (fingernail) or 12 weeks (toenail)

ref:medscape
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#6112681
<口訣> I-tra-co-...
(共 62 字，隱藏中）
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#3491019

Itraconazole

自皮膚與指甲之排泄較血液緩慢。皮膚感染時可於治療中止後2至4星期達到最佳的臨床及黴菌學反應；而指甲感染時則於治療中止後六至九個月達最佳反應。

5d2fc2498a8aa.jpg

取自藥物仿單~

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