阿摩線上測驗
16 下列抗黴菌藥物中，何者之作用機轉是抑制β(1-3)glucan，而影響黴菌細胞壁之形成？
(A) Fluconazole
(B) Caspofungin
(C) Amphotericin B
(D) Terbinafine
答案：登入後查看
統計： A(65), B(459), C(90), D(34), E(0) #417862
統計： A(65), B(459), C(90), D(34), E(0) #417862
詳解 (共 3 筆)
Bryan
#841351
Caspofungin is a lipopeptide antifungal drug .It is a member of a new class of antifungals termed the echinocandins. It works by inhibiting the enzyme -β-D-glucan synthase and thereby disturbing the integrity of the fungal cell wall. Caspofungin was the first inhibitor of fungal-β-D-glucan synthesis to be approved by the United States FDA.
靜脈注射給藥 治療全身性黴菌感染
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Bryan
#844280
Drug Classes → Anti-infectives → Antifungals → Echinocandins : Caspofungin
Echinocandins are a class of antifungal drugs that target the fungal cell wall. They are lipopeptide molecules that noncompetitively inhibit (1,3) beta-d-glucan synthase enzyme. This enzyme forms glucan, a major component of the fungal cell wall therefore by inhibiting its synthesis fungal cell walls are damaged.
Echinocandins are a class of antifungal drugs that target the fungal cell wall. They are lipopeptide molecules that noncompetitively inhibit (1,3) beta-d-glucan synthase enzyme. This enzyme forms glucan, a major component of the fungal cell wall therefore by inhibiting its synthesis fungal cell walls are damaged.
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