18.下列何者之negative inotropic effect最少，較不會造成心衰竭惡化？
(A)propranolol
(B)verapamil
(C)disopyramide
(D)amlodipine

會造成負向強心作用不可用在CHF者： 

1.心律不整藥class 1a的Disopyramide

2.心律不整class 1c的Flecainide、Propafenone

3.心律不整class 2的beta blocker（除了carve、biso、meto）

4.CCB（Amlodipine除外）

17.下列何種藥品會減弱心臟收縮力（negative inotropic effect），因而加重心臟衰竭？ 
(A)Celecoxib 
(B)Disopyramide 
(C)Rosiglitazone 
(D)Carbenicillin

Examples of negative inotropic agents include:

• Beta blockers
• Calcium channel blockers
  • Diltiazem
  • Verapamil
  • Clevidipine

Class IA antiarrhythmics such as

• Quinidine
• Procainamide
• Disopyramide

Class IC antiarrhythmics such as

• Flecainide
  ref: https://en.wikipedia.org/wiki/Inotrope#Negative_inotropic_agents

28.下列何者最不會惡化收縮性心衰竭（systolic heart failure）病人之症狀？ 
(A)amlodipine 
(B)propranolol 
(C)verapamil 
(D)disopyramide 

能用於CHF的CCB只有Amlodipine跟Felodipline

Baroreceptor reflex activation of sympathetic nerves and lack of direct negative cardiac effects can make dihydropyridines(-dipine) a less desirable choice for stable angina than diltiazem, verapamil or beta-blockers.