21 下列有關 digoxin 藥物交互作用之敘述，何者正確？
(A) Digoxin 併用 amiodarone，易造成 digoxin 血中濃度下降
(B) Digoxin 併用 clarithromycin，易造成 digoxin 血中濃度上升
(C) Digoxin 併用 cholestyramine，易造成 digoxin 血中濃度上升
(D) Digoxin 併用 furosemide，易造成血中鉀離子濃度上升

答案：登入後查看
統計： A(40), B(512), C(24), D(27), E(0) #412560

詳解 (共 3 筆)

#1432676
(A) Amiodarone抑制P-gp → digoxin 血中濃度↑
(B) Clarithromycin改變腸道菌叢 → digoxin 血中濃度↓
(C) Cholestyramine吸附作用 → digoxin 血中濃度↓
(D) Furosemide副作用低血鉀 → ↑digoxin中毒風險
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#2856364

Interactions between your drugs

Major

clarithromycin  digoxin

Applies to: clarithromycin, digoxin

Talk to your doctor before using digoxin together with clarithromycin.
Combining these medications may significantly increase the blood levels and effects of digoxin.

from:drugs.com


(A) Amiodarone抑制P-gp → digoxin 血中濃度↑

(B) Clarithromycin改變腸道菌叢、抑制P-gp → digoxin 血中濃度↑

(C) Cholestyramine腸胃道吸附digoxin → digoxin 血中濃度↓

(D) Furosemide副作用低血鉀 → ↑digoxin中毒風險


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#2822897

樓上有誤 Clarithromycin抑制腸菌分解 → digoxin↑

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