阿摩線上測驗
21.下列那一種藥物除了抑制慢速鉀電流（delayed vectifier patassium current, IKr）外，同時會增加慢速內流之鈉離子電流？
(A)Dofetilide
(B)Quinidine
(C)Sotalol
(D)Ibutilide
答案：登入後查看
統計： A(407), B(964), C(1371), D(2078), E(0) #537332
統計： A(407), B(964), C(1371), D(2078), E(0) #537332
詳解 (共 7 筆)
Ru
#1607548
22 下列抗心律不整藥物中，那一種藥物會抑制鈣離子電流及增加內向整流之鉀離子電流？
(A)Propranolol
(B)Adenosine
(C)Sotalol
(D)Ibutilide
答案：B
109
2
陳俊廷
#2862995
Ibutilide：Class III，抑制慢速鉀電流，同時會增加慢速內流之鈉離子電流
83
1
Bryan
#874429
Ibutilide is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm. It exerts its antiarrhythmic effect by induction of slow inward sodium current, which prolongs action potential and refractory period of myocardial cells. Because of its Class III antiarrhythmic activity, there should not be concomitant administration of Class Ia and Class III agents. 
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