21. Place the following in the order that they occur during transcription initiation:

1 - formation of open complex; 2 - formation of closed complex;

3 - promoter clearance; 4 - synthesis of about 10 nucleotides
(A) 1, 2, 3, 4.
(B) 2, 1, 4, 3.
(C) 2, 1, 3, 4.
(D) 3, 1, 2, 4.
(E) 3, 2, 1, 4.

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