25.Which statements accurately describe eukaryotic transcription initiation? (A) TFIID binds the TATA boх (B) RNA polymerase II requires general transcription factors (C) Enhancers must be located immediately upstream of promoters (D) Mediator integrates signals from activators (E) Promoter melting requires helicase activity in TFIIH

8. Which are the characteristics of genetic analysis? (A) Some of alleles can exhibit both recessive and dominant properties. (B) Dominant alleles are often the consequence of a mutation that causes some kind of gain of function. (C)Dominant mutations in certain genes are associated with a loss of function. (D)Dominant negative produces a phenotype similar to that obtained from a loss-of function mutation. (E)Recessive and dominant mutant alleles generally have opposite effects on gene function.

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