28.有關類癌(carcinoid)之敘述,下列何者錯誤?
(A)典型類癌(typical carcinoid)預後最佳
(B)類癌症後群(carcinoid syndrome)於典型類癌(typical carcinoid)很常見
(C)非典型類癌(atypical carcinoid)可能產生遠端轉移
(D)治療方式以手術切除為主
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統計: A(89), B(502), C(37), D(206), E(0) #3064393
統計: A(89), B(502), C(37), D(206), E(0) #3064393
詳解 (共 3 筆)
#6483052
| Feature | Typical Carcinoid | Atypical Carcinoid |
|---|---|---|
| Grade | Low-grade (well-differentiated) | Intermediate-grade (moderately differentiated) |
| Mitotic activity | ≤1 mitosis per 2 mm² | 2–10 mitoses per 2 mm² |
| Necrosis | Absent | Present (focal necrosis) |
| Aggressiveness | Indolent | More aggressive |
| Prognosis | Better | Worse than typical carcinoid |
| Metastatic potential | Low | Higher (but less than small cell carcinoma) |
| Location | Central or peripheral lung | Often central |
| Association with smoking | Not strongly associated | Not strongly associated |
| Immunohistochemistry | Chromogranin A, Synaptophysin, CD56 | Chromogranin A, Synaptophysin, CD56 |
Carcinoid syndrome (e.g., flushing, diarrhea) is rare in pulmonary carcinoids and more typical with GI carcinoids.
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