36 使用 triple test 來作為唐氏症產前篩檢。所謂 triple test 不包括下列何種檢驗?
(A)α-fetoprotein
(B)β-human chorionic gonadotropin
(C)Dimeric inhibin A
(D)Unconjugated estriol
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統計: A(50), B(29), C(588), D(93), E(0) #687766
統計: A(50), B(29), C(588), D(93), E(0) #687766
詳解 (共 1 筆)
#1059923
The Triple screen measures serum levels of AFP, estriol, and beta-hCG, with a 70% sensitivity and 5% false-positive rate. It is complemented in some regions of the United States, as the Quad screen (adding inhibin A to the panel, resulting in an 81% sensitivity and 5% false-positive rate for detecting Down syndrome when taken at 15–18 weeks of gestational age) and other prenatal diagnosis techniques, although it remains widely used in Canada and other countries. A positive screen indicates an increased risk of chromosomal abnormalities (and neural tube defects), and such patients are then referred for more sensitive and specific procedures to receive a definitive diagnosis, often prenatal diagnosis via amniocentesis, although the stronger screening option of cell-free fetal DNA screening (also popularly known as noninvasive prenatal screening) is frequently offered. The Triple test can be understood as an early predecessor to a long line of subsequent technological improvements. In some American states, such as Missouri, Medicaid reimburses only for the Triple test and not other potentially more accurate screening tests, whereas California offers Quad tests to all pregnant women. 參考資料
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