試題詳解

42. Consider a liver cell carrying out the oxidation of glucose under aerobic conditions. Suppose that we added a very potent and specific inhibitor of the mitochondrial ATP synthase, completely inhibiting this enzyme. Which of the following descriptions is(are)   correct  ?

1. The rate of oxygen consumption will increase. 

2. ATP production in the cell will quickly drop to zero.

3. The citric acid cycle will speed up to compensate.

4. Mitochondrial ATP synthesis will cease, but to compensate, cells will accelerate the production of ATP by glycolysis, preventing ATP levels from dropping to zero.

5. The cell will switch to fatty acid oxidation as an alternative to glucose oxidation.
(A) 1 and 5 are correct.
(B) 3 and 4 are correct.
(C) Only 2 is correct.
(D) Only 4 is correct.
(E) Only 5 is correct.