45.Opioid analgesics以下列何種方式給藥,可以提供最佳的疼痛緩解?
(A)IM
(B)IV PCA(病人自控式止痛劑)
(C)IV
(D)epidural PCA
統計: A(17), B(2361), C(241), D(2768), E(0) #2039082
詳解 (共 9 筆)
樓上資料很完整,但我還是不懂BD怎麼選,甚麼是最佳的疼痛緩解?
根據目前訊息,我猜 →
epidural PCA:適合做continuous basal infusion
IV PCA:bolus opioid doses
【uptodate】
As with intermittent opioid administration, the patient’s previous long-acting opioid should be continued, if possible.
If unable to do so, a continuous basal infusion on a PCA can be calculated to equal the patient’s previous baseline long-acting opioid dose.
The continuous rate should be reevaluated daily and decreased if the pain level decreases.
Clinician decision-making about when and how to add bolus opioid doses to the long-acting basal dose depends on the pattern and etiology of the acute pain.
IV PCA:感覺到痛可以自己控制,意識混亂不適用
就用最直觀的去想,等你痛了在按IV PCA還要等血中濃度夠,所以epidural PCA比較好
硬脊膜外止痛藥(Epidural narcotics)
常用於無痛分娩,硬脊膜外腔麻醉及其術後之疼痛控制
|
特性 |
藥物 |
機轉 |
onset |
duration |
|
高脂溶性 |
fentanyl、sufentanil |
注入硬脊膜腔之藥物,會滲透到脊髓液再穿透過細胞壁和脊髓背根之嗎啡接受器結合,如此可減少局部麻醉藥之用量 |
快 |
短 |
|
非脂溶性 |
morphine 類 |
作用機轉在腦幹的細胞核 |
慢 |
長 |