46. Regarding the actions of spinal and supraspinal analgesia for opioids, which of the following statement is most likely: (A) Opioid receptors are mostly located at a predominantly 70% postsynaptic location on the central terminals of only small diameter nociceptive primary afferents. (B) The contribution of kappa, delta and mu receptors to the total opiate binding throughout the spinal cord is estimated to be delta ＞ mu ＞kappa. (C) Opioids inhibit OFF cells via GABA neurons and activate ON cells in the rostromedial medulla (RVM) leading to changes in spinal descending controls. (D) Nitric oxide (NO) is required for the 5-HT-mediated inhibition of PAG output and reversal of antinociception. (E) Fibers descending from the PAG to the dorsal horn of the spinal cord are mostly enkephalinergic, glycinergic and GABAergic.

46. Regarding the actions of spinal and supraspinal analgesia for opioids, which of the following statement is most likely:
(A) Opioid receptors are mostly located at a predominantly 70% postsynaptic location on the central terminals of only small diameter nociceptive primary afferents.
(B) The contribution of kappa, delta and mu receptors to the total opiate binding throughout the spinal cord is estimated to be delta ＞ mu ＞kappa.
(C) Opioids inhibit OFF cells via GABA neurons and activate ON cells in the rostromedial medulla (RVM) leading to changes in spinal descending controls.
(D) Nitric oxide (NO) is required for the 5-HT-mediated inhibition of PAG output and reversal of antinociception.
(E) Fibers descending from the PAG to the dorsal horn of the spinal cord are mostly enkephalinergic, glycinergic and GABAergic.

答案：登入後查看
統計： A(1), B(0), C(0), D(2), E(0) #3160582

詳解 (共 1 筆)

MoAI - 您的AI助手

B1 · 2025/11/04

#7024438

1. 題目解析本題涉及脊髓及超脊髓（s...

(共 931 字，隱藏中）

前往觀看

42. Which one of the following statement is wrong? (A) The person who has a chronic pain condition resides in a complex and costly world that is populated not only by themselves but also by their significant others, including health care providers, employers, and third-party payers. (B) People with chronic pain may feel that their health care providers, employers, and even family members are blaming them when their condition fails to respond to treatment as expected. (C) In the absence of cure or even substantial relief, individuals experiencing chronic pain may withdraw from contacts； lose their sources of income； alienate family, friends, and coworkers； and become more and more isolated, despondent, depressed, and, in general, demoralized. (D) Psychosocial and behavioral factors play an insignificant role in the experience, maintenance, and exacerbation of pain and potentially even the cause. (E) Because some level of pain persists in the majority of people with chronic pain regardless of treatment, self-management is an important complement to biomedical approaches.

詳解 (共 1 筆)

其他試題