48.下列檢驗方法與診斷疾病之配對，何者錯誤？
(A)Platelet serotonin release assay：heparin-induced thrombocytopenia
(B)ADAMTS-13 assay：thrombotic thrombocytopenic purpura
(C)Platelet-associated IgG：immune thrombocytopenic purpura
(D)Platelet factor 4 antibody ELISA：anti-phospholipid syndrome

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統計： A(462), B(185), C(175), D(921), E(0) #3133895

詳解 (共 6 筆)

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了解疾病病理 有助於配對檢驗方法 La...
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(A) Platelet seroton...
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如果不知道Platelet factor...
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Platelet serotonin release assay：heparin-induced thrombocytopenia
參考：https://www.ncbi.nlm.nih.gov/books/NBK482330/
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HIT：
  1. PF4 ELISA陽性→血清素釋放試驗做確認診斷
  2. 血清素釋放試驗陽性則確診HIT，若PF4 ELISA陽性但血清素釋放陰性也是排除HIT
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關於檢測HIT所使用的PF4 ELISA跟血清素釋放試驗(SRA)：
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if the PF4 ELISA is positive, the result should be confirmed with the SRA, the gold standard test for confirming HIT with high sensitivity and specificity. Unlike ELISA, which detects the presence of antibodies, the SRA is a functional test, which detects the activation of platelets in the presence of antibodies. A donor platelet that becomes activated in the presence of heparin and a sample of the patient's blood (containing IgG) will release serotonin.
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A positive SRA confirms the diagnosis of HIT, and negative SRA rules out HIT, even in the setting of a positive ELISA.
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dRVVT : anti-phospholipid syndrome

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