試題詳解

5. Which one of the following statements is wrong?
(A) Pain and hyperalgesia arise in part from the action of inflammatory mediators on the peripheral terminals of nociceptive neurons.
(B) The list of inflammatory mediators may include arachidonic acid metabolites, bradykinin, adenosine triphosphate and nitric oxide.
(C) A series of inflammatory cytokines and chemokines, such as tumor necrosis factor-α and interleukin-1β, and growth factors, particularly nerve growth factor, are capable of changing the response properties of pain-signaling neurons.
(D) The inflammatory mediators may activate nociceptive terminals or regulate gene expression of nociceptors.
(E) All of the above are correct.